Vascular calcification, vitamin K, phosphate binders and MGP

Authors
Category Primary study
Registry of TrialsNetherlands Trial Register
Year 2014
INTERVENTION: treatment with calciumcarbonate or lanthanum carbonate with supplemantation of vitamin K CONDITION: Vascular calcification, Phosphate binders, Chronic renal failure, Vitamin K, MGP ; ; PRIMARY OUTCOME: Absolute difference between serum level of dp‐ucMGP and PIVKA II at week 8 between phosphate binder groups (between group analysis). SECONDARY OUTCOME: Absolute change from baseline to end of treatment period for lanthanumcarbonate group and calciumcarbonate group, respectively (longitudinal within group analysis). Association between change in dp‐ucMGP and PIVKA II. Change in dp‐ucMGP between week 16 and 20. INCLUSION CRITERIA: Haemodialysis patients aged 18 years or above without the prospect of renal function recovery, planned renal transplantation, and life expectancy longer than six months.
Epistemonikos ID: f152f89b69015833d50c5fba581d4a922eb6fe9f
First added on: Aug 23, 2024