A phase II study of percutaneous trans-esophageal gastric tubing for malignant gastrointestinal obstruction (JIVROSG-0205)

INTERVENTION: Under local anesthesia and fluoroscopy or ultrasonic guidance, a percutaneous route to cervical esophagus is made by direct puncture to the intra‐esophageal balloon inserted via nasal or oral route, and then, a drainage tube is placed from the neck surface to the stomach using this route. CONDITION: Malignant gastrointestinal obstruction PRIMARY OUTCOME: Improvement of subjective symptoms compared to previous nasal tubing. SECONDARY OUTCOME: Adverse events and feasibility of procedure INCLUSION CRITERIA: 1) No expectation for removal of nasal tube caused by persistent and malignant gastro‐intestinal obstruction. 2) No pathological condition around cervical esophagus. 3) Adequate cardiac, hepatic, renal, respiratory, and bone marrow functions. 4) Eastern Cooperative Oncology Group (ECOG) performance status of 0 to 3. 5) Expected survival more than 4 weeks. 6) Written informed consent.