Acupuncture treatment of breast cancer after chemotherapy in patients with cognitive impairment caused by 'disorder of qi and blood': a randomized single-blind study

INTERVENTION: The 100 eligible participants are randomly allocated to two different groups: 1. Treatment group: acupuncture will be given at Zusanli (ST 36) Point?Xuhai Point?Tanzhong Point?Zhongwan Point?Qihai (CV 6) Point?Baihui(GV 20) Point?Fengfu Point?Xinshu(bl 15) Point?Yixi (bl 45) Point?Tongli (ht 5) Point and Zhaohai (KI 6) Point twice a week for 2 months. The patients receive assessments every month during the treatment and the second month and the fourth month after the treatment. 2. Control group: acupuncture will be given at five feint points twice a week for 2 months. CONDITION: Breast cancer after chemotherapy in patients with cognitive impairment ; Cancer PRIMARY OUTCOME: Using the Montreal Cognitive Assessment (MoCA)to assess cognitive function. To observe the cognitive ability of patients with breast cancer after chemotherapy with cognitive dysfunction. The outcome measure above will be assessed before the treatment, at 1 month and 2 months during the treatment; the assessments will be repeated at the second and fourth months after the treatment. SECONDARY OUTCOME: 1. Using the Mini‐mental State Examination to assess immediate memory, attention, computing power, etc.; 2. Using the EORTC QLQ‐30 to assess the quality of life.; The outcome measures above will be assessed before the treatment, at 1 month and 2 months during the treatment; the assessments will be repeated at the second and fourth months after the treatment.; 3. Safety assessment. Acupuncture treatment can lead to curved needle, needle breakage and adverse reactions such as subcutaneous hematoma, therefore we will evaluate the safety of acupuncture. INCLUSION CRITERIA: 1. Patients with breast cancer at the age of 25 to 55 years old 2. Neuropsychological evidence of cognitive impairment 3. In the 28 months after chemotherapy according to DSM‐IV diagnosis of cognitive impairment 4. According to the MoCA score < 26 points, determining with cognitive dysfunction 5. There is a causal relationship between chemotherapy and cognitive impairment, and except for other diseases 6. The type of traditional Chinese medicine is a disorder of qi and blood 7. At least one field of cognitive dysfunction 8. Diagnosis of dementia standard has not yet arrived 9. Have signed informed consent