Immediate Analgesic and Sustained Effects of Manual Release Combined with Therapeutic Ultrasound on Myogenic Temporomandibular Disorders: a Randomized, Sham-Controlled, Assessor-Blinded Clinical Trial

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: control group:manual therapy;experimental group:Ultrasound combined with manual therapy; CONDITION: Temporomandibular joint disorders (TMD) PRIMARY OUTCOME: NRS score; SECONDARY OUTCOME: Patient Global Impression of Change;JFLS‐8 score;Resting NRS Score;Mandibular movement function;Responder rate;Pressure Pain Threshold (PPT) and Difference Between Healthy and Affected Sides (?PD);Masticatory function;Fricton Temporomandibular Joint Dysfunction Index;Opening Deviation;Maximum Voluntary Opening (MMO) Pain‐Free Maximum Opening (PF‐MMO) Maximum Passive Opening; INCLUSION CRITERIA: 1.meeting the diagnosis of "myalgia" according to Axis ? of the internationally recognized Diagnostic Criteria for Temporomandibular Disorders (DC/TMD); 2. aged 18 to 40 years; 3. presenting with unilateral masticatory muscle pain as the primary complaint, with a Numerical Rating Scale (NRS) score for pain during chewing >=3; 4. disease duration >= 1 month; 5. able to comprehend the content of the questionnaires and cooperate in completing all assessments.
Epistemonikos ID: f04d040e4a990d67086e9208951d6780ad7beefc
First added on: Oct 08, 2026