The use of metformin in patients with polycystic ovarian syndrome requiring treatment with in vitro fertilisation (IVF)

INTERVENTION: Group A will be given 500 mg metformin TDS for 1 month prior to their treatment. Group B will not be treated with metformin. Both groups will undergo standard IVF treatment. CONDITION: Urological and Genital Diseases: Polycystic ovarian syndrome (PCOS) ; Urological and Genital Diseases ; Polycystic ovarian syndrome (PCOS) PRIMARY OUTCOME: 1. Total number of folicles reaching 18 mm; 2. Number of eggs obtained, number and quality of mature eggs, fertilisation rates; 3. Total number of embryos, number and quality of embryos replaced and number of embryos frozen; 4. Biochemical pregnancies, clinical pregnancies; 5. Number of cycles abandoned for poor response and over response; 6. Number of cases of ovarian hyperstimulation in each group SECONDARY OUTCOME: Not provided at time of registration INCLUSION CRITERIA: Patients with PCOS