Evaluation of Dupilumab in Children With Uncontrolled Asthma

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2017
Primary Objective: To evaluate the efficacy of dupilumab in children 6 to less than (\<) 12 years of age with uncontrolled persistent asthma. Secondary Objective: To evaluate in children 6 to \<12 years of age with uncontrolled persistent asthma: * The safety and tolerability of dupilumab. * The evaluate the effect of dupilumab in improving participant reported outcomes including health related quality of life. * The dupilumab systemic exposure and incidence of anti-drug antibodies. * The evaluate the association between dupilumab treatment and pediatric immune responses to vaccines: any vaccination for tetanus, diphtheria, pertussis and/or seasonal trivalent/quadrivalent influenza vaccine.
Epistemonikos ID: eee0c68ef6cc08b0d4fe189847eb5973894256ac
First added on: May 17, 2024