Safety, Tolerability and Effects of Mannitol in Parkinson's Disease

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2018
Parkinson's disease is a progressive neurodegenerative disease that causes disabling motor and cognitive impairments. Currently, no disease‐modifying therapy exists for this disease. Mannitol, a naturally‐occurring substance, which is commonly used as sweetener, was offered as such agent. In this phase II, safety, tolerability‐based dose finding, and efficacy study, mannitol or placebo (dextrose) in escalating doses will be given to patients with Parkinson's disease for 36 weeks.
Epistemonikos ID: eec7d792b61cbac764d1a29ebc38c23dd6f4bc70
First added on: May 22, 2024