Effect of Nigella sativa seed oil in treatment of hypertension

Authors
Category Primary study
Registry of TrialsIranian Registry of Clinical Trials
Year 2013
INTERVENTION: Control group will orally receive 5 ml /day of Sunflower seed oil for 8 weeks in addition to their current treatment regimen. Sunflower seed oil, which is used as a placebo, has no real effect on blood pressure. This oil has very similar physical characteristics to NS oil. Only the code written on the containers are different from each other. Frequency and duration of using placebo oil in the control group are absolutely the same as NS oil in the intervention group. Intervention 1: The patients in Intervention group will orally receive 5 ml /day of Nigella Sativa seed oil for 8 weeks in addition to their current treatment regimen. Intervention 2: Control group will orally receive 5 ml /day of Sunflower seed oil for 8 weeks in addition to their current treatment regimen. Sunflower seed oil, which is used as a placebo, has no real effect on blood pressure. This oil has very similar physical characteristics to NS oil. Only the code written on the containers are different from each other. Frequency and duration of using placebo oil in the control group are absolutely the same as NS oil in the intervention group. The patients in Intervention group will orally receive 5 ml /day of Nigella Sativa seed oil for 8 weeks in addition to their current treatment regimen. Treatment ‐ Drugs CONDITION: Essential (primary) hypertension Hypertensive patients. ; Essential (primary) hypertension PRIMARY OUTCOME: Diastolic Blood pressure. Timepoint: During the intervention (every week). Method of measurement: blood pressure manometer. Malondialdehyde [MDA] in serum. Timepoint: Before and 8 weeks after intervention. Method of measurement: Spectrophotometry. Systolic Blood pressure. Timepoint: During the intervention (every week). Method of measurement: blood pressure manometer. SECONDARY OUTCOME: Blood sugar. Timepoint: Before and 8 weeks after the intervention. Method of measurement: Biochemical test. Lipid profile. Timepoint: Before and 8 weeks after the intervention. Method of measurement: Biochemical test. INCLUSION CRITERIA: INCLUSION CRITERIA: Hypertensive patients with SBP/DBP = 140/90 mmHg who do not suffer from heart, kidney and liver failure were eligible for inclusion. Exclusion criteria: Patients who smoke and patients who consume antioxidant products aren't enrolled in the study.
Epistemonikos ID: eebccd8f3245c8fb01e886a964cf323b3ef3ec14
First added on: Apr 23, 2019