Can squeezing blood from the umbilical cord into the baby reduce death and illness in premature babies?

Authors
Category Primary study
Registry of TrialsISRCTN registry
Year 2018
INTERVENTION: This study is held in a single centre. After informed consent has been provided the parents, the baby will be randomly assigned to one of two groups, the milking group and the clamping group. After the birth, an obstetrician will cut the umbilical cord leaving at least 20 cm. For the cord milking group, the baby will be placed under the radiant warmer and the umbilical cord raised and milked from the cut end towards the baby with a speed of 10 cm/s and clamped at 2–3 cm. The milking will be performed by a neonatologist while resuscitation will be conducted by an accompanying paediatrician certified in the Neonatal Resuscitation Program (NRP) and the nurse attending the delivery. For the control arm, the umbilical cord was initially cut to 20 cm and then was clamped near the umbilicus and cut without cord milking. CONDITION: Preterm baby (less than 30 weeks of gestational age) ; Pregnancy and Childbirth PRIMARY OUTCOME: ; 1. Neonate's hemoglobin level at admission; 2. Neonate's hematocrit at admission; 3. Neonate's mean arterial pressure at admission; 4. Administration of inotropic agents in first 72 h post‐birth; All data will be taken from medical records.; SECONDARY OUTCOME: ; 1. Rate of death before post‐menstrual age (PMA) of 36 weeks assessed by reviewing the patient’s medical records; 2. Rate of bronchopulmonary dysplasia assessed by reviewing the patient’s medical records; 3. Rate of all‐stage intraventricular hemorrhage assessed by reviewing the patient’s medical records; 4. Rate of severe intraventricular hemorrhage assessed by reviewing the patient’s medical records; 5. Rate of necrotizing enterocolitis assessed by reviewing the patient’s medical records; 6. Rate of retinopathy of prematurity assessed by reviewing the patient’s medical records; Neonates will be followed up from birth until first discharge from hospital.; INCLUSION CRITERIA: Preterm (born at less than 30 weeks of gestational age)
Epistemonikos ID: ee7e736956a461cce58ef56aec432e9936f9fa21
First added on: Aug 24, 2024