A study comparing Plasmalyte and Ringers Lactate for preventing acute kidney injury in elderly patients undergoing orthopedic surgery

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Intraoperative plasmalyte fluid: Intraoperative intravenous fluid and its buffering agents my provide some beneficial properties towards kidney protection Control Intervention1: Intraoperative ringers lactate fluid: Lactate as buffer differs from plasmalyte fluid and it would alter the outcomes CONDITION: Health Condition 1: O‐ Medical and Surgical PRIMARY OUTCOME: Incidence of peri operative acute kidney injuryTimepoint: T0 baseline ; T1 24hours Post surgery ; T2 48 hours ; T3 72 hours SECONDARY OUTCOME: Association of intraoperative hemodynamics and perioperative acute kidney injury ; To compare perioperative changes in serum creatinine and urine output between 2 groupsTimepoint: Baseline ; Intraoperatively every 5 minutes ; 24hours ; 48 hours ; 72hours INCLUSION CRITERIA: Age more than 60 years Either gender Normal preoperative kidney function ASA I , II Duration of surgery less than 4hours
Epistemonikos ID: ee0e7e92d32f100a255217640072028be864e530
First added on: Oct 08, 2026