Effectiveness of a Mindfulness-Based Intervention for Pain Management in Patients With Multiple Sclerosis (MPIMS)

The goal of this clinical trial is to evaluate whether a mindfulness‐based interventionis effective for reducing pain in adults with multiple sclerosis. It will also assesswhether this intervention improves other symptoms commonly associated with pain, such asfatigue, sleep disturbances, anxiety, depression, and quality of life.The main questions it aims to answer are: ‐ Does a mindfulness‐based intervention reduce pain intensity in people with multiplesclerosis? ‐ Does the intervention improve fatigue, sleep quality, emotional well‐being, qualityof life? ‐ Does the effectiveness of the intervention differ according to the type of painexperienced by participants? Researchers will compare a mindfulness‐basedintervention with an educational program to determine whether mindfulness providesadditional benefits for pain management in people with multiple sclerosis.Participants will: ‐ Be randomly assigned to either the mindfulness intervention group or the educationalcontrol group. ‐ Complete assessments before the intervention, immediately after the intervention,and at 1‐month and 3‐month follow‐up visits. ‐ If assigned to the mindfulness group, attend eight weekly 2.5‐hour group sessionsplus one 6‐hour retreat, either in person or online. ‐ If assigned to the control group, attend two 2‐hour educational sessions during thestudy period. ‐ Complete questionnaires evaluating pain, fatigue, physical function, anxiety,depression, sleep quality, quality of life, and mindfulness throughout the study.