A Study Comparing Pirfenidone Tacrolimus and Silicone Gel for Improving the Appearance of Healed Scars in Adults

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Group A Pirfenidone and Silicone gel: Topical pirfenidone gel in combination with Topical silicone gel 6 months Intervention2: Group B Tacrolimus and Silicone gel: Topical tacrolimus ointment in combination with topical silicone gel 6 months Control Intervention1: Group C Silicone gel: Topical silicone gel 6 months CONDITION: Health Condition 1: L768‐ Other intraoperative and postprocedural complications of skin and subcutaneous tissue PRIMARY OUTCOME: The primary outcome measure will be the change in Modified Vancouver Scar Scale total score from baseline to week 24Timepoint: Week 0 ; week 4 ; Week 12 ; Week 24 SECONDARY OUTCOME: Patient and Observer scar assessment scales ; Standardized digital photography and colorimetry ; DLQI ; Adherence monitoring by MMAS 8 scoring ; Adverse Event monitoringTimepoint: Week 0 ; Week 4 ; Week 12 ; Week 24 INCLUSION CRITERIA: Age 18 to 70 years stable post operative scars arising from minor office based procedures involving clean incisions lesser than 2 to 3 cm scars on non contractile sites and scars post complete wound healing with minimum or no contamination
Epistemonikos ID: ed1e2923358d84dbe84de923e0d8c48a984f32a7
First added on: Oct 08, 2026