Comparison of Diagnostic Performance between Endoscopic Ultrasound-Guided Through-the-Needle Biopsy Forceps Biopsy (EUS-TTNB) and Fine-Needle Aspiration (EUS-FNA) for Pancreatic Cystic Lesions: a Prospective, Multicenter, Randomized Controlled Trial

INTERVENTION: EUS‐TTNB group:Endoscopic ultrasound‐guided through‐the‐needle biopsy;EUS‐FNA group:Endoscopic ultrasound‐guided fine‐needle aspiration; CONDITION: Pancreatic cystic lesions PRIMARY OUTCOME: Diagnostic rate; SECONDARY OUTCOME: The amount of tissue obtained from the specimen; INCLUSION CRITERIA: 1.Chinese patients aged 18–85 years; 2.Diagnosis or suspicion of a pancreatic cystic lesion based on at least one imaging examination, including CT, MRI, or PET‐CT; 3.Presence of at least one high‐risk feature for malignancy: maximum lesion diameter =3 cm, mural nodule or solid component, main pancreatic duct dilation >5 mm, abrupt pancreatic duct cutoff with distal pancreatic atrophy, lymphadenopathy, lesion growth rate >3 mm/year, elevated CA19‐9, or jaundice or acute pancreatitis caused by the cyst; 4.No previous histopathological diagnosis; 5.Voluntary participation and provision of written informed consent;