Clinical effect of luekotriene receptor antagonist on provocation symptom induced by Japanese cedar pollene antigen disc and grope for clinical marker of nasal obstraction

INTERVENTION: It is given the test capsule containing leukotriene receptor antagonist(montelukast Na 10mg): 1 capsule per 1 day for a week before the Japanese cedar pollene provocation test. It is given the placebo capsule containing lactatose powder: 1 capsule per 1 day for a week before the Japanese cedar pollene provocation test. CONDITION: Japanese cedar pollinosis PRIMARY OUTCOME: Effect of leukotriene receptor antagonist SECONDARY OUTCOME: Serum and urinary oxidized stress substances concentration. Nicotid Oxide concentration in nasal cavity INCLUSION CRITERIA: CAP‐RAST against Japanese cedar pollen over class 2 whith clinical history of allergic symptoms during the Japanese cedar pollen season.