Bioavailability of Vagantin® Coated Tablets Relative to an Oral Methantheline Bromide Solution

Category Primary study
Registry of Trialsclinicaltrials.gov
Year 1999
The primary objective of the study is: •To describe extent and rate of absorption of methantheline after single oral dose administration of Vagantin® coated tablets (Test) in comparison to a methantheline bromide solution (Reference) The secondary objectives of the study are: * To determine elimination the half-life of methantheline bromide * To describe the effects of Test and Reference on salivation, accommodation, pupil response, blood pressure and heart rate * to assess frequency and intensity of adverse drug reactions
Epistemonikos ID: ec2fb9e43a021db70de36569160536b7835a3d28
First added on: May 06, 2024