Sinus floor augmentation with microstructured BCP granules

INTERVENTION: Patients will undergo sinus floor augmentation with either autologous bone graft or with micro‐structured BCP granules. CONDITION: Maxillary atrophy, Maxillary sinus floor augmentation, Sinus pneumatization ; ; PRIMARY OUTCOME: Percentage of new bone formation in the augmented sinus floor by histomorphometrical analysis of biopsy specimens at 5 months of follow up. SECONDARY OUTCOME: ‐ Implant survival rate and adverse events during 17 months of follow up. ; ; ‐ Augmented bone height as measured by CBCT at 5, 11 and 17 months of follow up. ; ; ‐ Implant stability quotient (ISQ) as measured by resonance frequency analysis (RFA) at 5 months (primary stability) and 11 months of follow‐up. ; ; ‐ Scoring of gingival index, supra‐gingival plaque index, and dichotomous bleeding index 17 months after surgery. ; ; ‐ Probing depth of implant and adjacent teeth (buccal, palatinal, distal, mesial) at 17 months after surgery. ; ; ‐ Pain by the Visual Analogue Scale (VAS‐score) ; INCLUSION CRITERIA: ‐ Male or female patients aged 18‐75 years ‐ Patient is willing to give informed consent to participate in the study ‐ Patient qualifies for sinus augmentation surgery ‐ Presence of a unilateral or bilateral (partial) maxillary edentulism involving the premolar/molar areas ‐ Presence of a residual posterior maxillary bone height between 2 and 6 mm