Effect and efficiency of microneedle radiofrequency in the treatment of periorbital wrinkles: a prospective, randomized, split-face study

INTERVENTION: long pulse‐width group :long pulse‐width microneedle radiofrequency;short pulse‐width group:short pulse‐width microneedle radiofrequency; CONDITION: wrinkle PRIMARY OUTCOME: The Fitzpatrick Wrinkle Classification System,FWCS; SECONDARY OUTCOME: Lemperle periorbital wrinkle scale;Global Aesthetic Improvement Score, GAIS;area of the periorbital wrinkle; INCLUSION CRITERIA: periorbital wrinkles, Fitzpatrick score>3, 25‐65 years old, male/female; haven't got any treatment of periorbital wrinkles in the last year; written informed consents were taken from all patients or their guardians; accept the randomized, split‐face design and follow‐up schedule.