Psilocybin-Assisted Psychotherapy in Treating Irritable Bowel Syndrome (IBS)

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2025
This study will serve as a pilot randomized controlled trial to assess the feasibility of Psilocybin-Assisted Psychotherapy (PAP) in Treating Irritable Bowel Syndrome (IBS). Patients with severe IBS will undergo 3 pre-psychotherapy sessions with two licensed and trained psychedelic therapists, then will be randomized to undergo a guided psychotherapy session with single 25 mg oral \"high\" dose of psilocybin or a single 100 mg dose of niacin (active placebo) and attend 4 post-therapy integration sessions.
Epistemonikos ID: eb8979cd5534cb52c87f7aa70dd17384fa4a119b
First added on: Feb 01, 2025