Effects of BCG on Immune Response

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2014
In the present study, we want to investigate whether BCG-vaccination enhances the innate immune response in humans in vivo during (single) human endotoxemia. In a future experiment we will investigate whether BCG-vaccination can reverse the tolerant state observed upon a second LPS administration. Our goal is to ultimately translate our results into clinic applications to reverse for example sepsis-induced immunoparalysis.
Epistemonikos ID: eb4462f0aae09300bac674520ab88e71ba2d1292
First added on: May 11, 2024