Study to Assess Various Sunitinib Schedules in Renal Cell Carcinoma

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2016
Patients who are candidates for first line treatment with Sunitinib 50mg 4/6 regimen in accordance with the Marketing Authorisation who meet the inclusion/exclusion criteria will be offered participation in this study during the consultation as part of their usual care. The patients will be included before Sunitinib treatment is started. Thereafter, sunitinib is initiated 50 mg/day; regimen 4/6 (Marketing Authorisation Indication), 4 weeks \"on \" alternating with 2 weeks \"off \" As soon as a dose or schedule adjustment is required, regardless of cause, the patient will be randomised 1/1: * Either into arm A and will receive 37.5mg of Sunitinib per day by the 4/6 regimen (in accordance with the Marketing Authorisation); 4 weeks \"on \" alternating with 2 weeks \"off \" * Or into arm B and will receive 50mg of Sunitinib per day by the 2/3 regimen (investigational arm); 2 weeks \"on \" alternating with 1 week \"off \"
Epistemonikos ID: eaee90512584bcb312830cb629c30d37b7118955
First added on: May 12, 2024