Tamsulosin as Adjuvant Treatment Prior to Endoscopic Ureterolithotomy

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2018
Endoscopic treatment of urolithiasis has increased during the last several years. Adrenergic receptors have been described mainly in the distal ureter. Blockage of adrenergic receptors has been associated to a decrease in ureteral resistance. In this study the investigators hypothesized that alpha blockers are associated to a decrease in ureteral resistance with an increase in successful endoscopic management of urolithiasis. Only patients with urolithiasis undergoing to endoscopic treatment are offered to participate. Patients are randomized between placebo arm or tamsulosin 0.4 mg/day. Demographic characteristics, stones characteristics and information related to surgery are recorded. Main study outcome is stone free rate and successful insertion of semirigid ureteroscope 8,0 ‐ 9,8 Fr. All patients are follow‐up for 30 days after surgery.
Epistemonikos ID: ea8b5591035bd0a3ad605cdd9595b2bb6a316698
First added on: May 21, 2024