Targeting Immune Modulation in High Grade Serous Carcinoma: Combined Effects of Chemotherapy and Atorvastatin

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
The goal of this clinical trial is to learn how atorvastatin in patients with advancedhigh grade serous cancer of the ovary, fallopian tube, or peritoneum changes the tumorimmune environment. The main question it aims to answer is: ‐ Does atorvastatin combined with standard of care chemotherapy and surgery changesthe number of tumor‐promoting macrophages in the tumor microenvironment ‐ Researchers will compare standard of care chemotherapy and surgery to see if thereis a difference in tumor promoting macrophages. ‐ Participants will take atorvastatin (daily pill) alongside their standard treatment.
Epistemonikos ID: e91c4725d13b6707609a024f5c67db09793133c6
First added on: Sep 12, 2026