Open-label, single-center, randomized and parallel-group study to compare the effect of Hydrofluoroalkane-134a beclomethasone dipropionate and Chlorofluorocarbon beclomethasone dipropionate on small airways involvement in asthma assessed using impulse oscillometry system.

INTERVENTION: Hydrofluoroalkane‐134a beclomethasone dipropionate 200 mcg bids 12 weeks Chlorofluorocarbon dipropionate 400 mcg bid 12 weeks CONDITION: Bronchial asthma PRIMARY OUTCOME: Parameters of impulse oscillometry system. SECONDARY OUTCOME: 1 Symptoms; 2 Wheezing on auscultation; 3 Methacholine airway responsiveness; 4 Pulmonary function; 5 Lung volume measurement; 6 Inflammatory biomarkers of induced sputum and peripheral blood; 7 Safety INCLUSION CRITERIA: Inhaled corticosteroids‐naive mild‐to‐moderate asthmatic patients