Effect of Propolis paste as compared to Calcium hydroxide on post-root canal treatment pain when inserted in root canals of infected teeth

INTERVENTION: Control group: Calcium hydroxide Intervention group: Propolis paste Non‐probability sampling will be done for sample recruitment and simple randomization for group allocation. Random group allocation will be computer generated. with equal randomization (1:1). The patients and the principal researcher will be blinded from the type of intracanal medicament inserted. Patient attending the diagnosis department of the hospital with complaint of pain and having necrotic teeth found on examination, requiring standard non‐surgical endodontic treatment are selected by non probability sampling for the study with his/her consent. Participants are randomly allocated to one of two groups by computer generated simple randomisation. Group 1 (Control group): In the 1st visit of non surgical endodontic therapy, the standard procedure is performed until root canal preparation is completed. Then participants receive calcium hydroxide as an intracanal medicament inserted in the canal. This is supplied in a paste like consistency by the manufacturer and approximately 2.5 mg of the medication is used in each canal. This is inserted with the help of lentulo‐spirals. They are only inserted once and then temporary fillings are done inside the tooth. Group 2 (Intervention group): In the 1st visit of non surgical endodontic therapy, the standard procedure is performed until root canal preparation is completed. Then participants receive Propolis paste as an intracanal medicament inserted in the canal. Propolis paste is made by mixing 1.5 mg of propolis powder with 1 ml of normal saline and then is inserted into the root canal. This is inserted with the help of lentulo‐spirals. They are only inserted once and then temporary fillings are done inside the tooth. Participants are followed up after their first visit to mark their pain intensity (score) pre‐operatively, then at four hours, 12 hours, 24 hours, 48 hours and 72 hours. Participants are then recalled after a week, and their pains s CONDITION: Domain in healthcare is dentistry and the condition we will be studying is Necrotic teeth with symptomatic apical periodontitis ; Oral Health ; Necrotic teeth with symptomatic apical periodontitis PRIMARY OUTCOME: 1. Pain score is recorded by the patient using the Visual Analogue Scale (VAS scale) at four, 12, 24, 48 and 72 hours; 2. Number of patients reaching the full followup period without taking oral analgesic is measured using the Visual Analogue Scale (statistically analysed during processing (after VAS scales are collected from all of the patients) to know how many patients reached the full follow up period of 72 hours without taking any oral analgesic) at 72 hours SECONDARY OUTCOME: Types of oral analgesic is measured using VAS scale (which is based on oral analgesics prescribed according to differing intensities of pain) and evaluating what type of analgesics are taken the most in each group at 72 hours INCLUSION CRITERIA: 1. Aged 20‐40 years 2. Both male and female both 3. Single rooted Necrotic teeth with symptomatic periapical periodontitis having visible periapical widening or radiolucency without bone expansion (PAI index 3 and 4) 4. Teeth with favorable root morphology 5. Teeth with closed apex