Efficacy of locally placed papaya leaf extract tablet when compared with oral systemic NSAIDS on post operated sequelae of impacted madibular third molar-A Randomised controlled clinical trial

INTERVENTION: Intervention1: Locally placed Carica papaya leaf extract tablet: Routine surgical impaction will be done following the standardized steps then in GRP 1 patients Carica papaya leaf extract soaked in Abgel will be placed in the extraction socket followed by routine closure with 3‐O BB silk suture will be done.ation protocol and steps Control Intervention1: Oral Systemic NSAID S: Routine surgical impaction will be done following the standardized steps then in GRP 2‐ Routine closure of the extraction socket with 3‐O BB silk suture will be done. CONDITION: Health Condition 1: K011‐ Impacted teeth PRIMARY OUTCOME: Compare and evaluate post operative oedema after placement of Carica papaya leaf extract in the socket or after prescribing systemic NSAID S following surgical extraction of third molar ; Compare and evaluate wound healing after placement of Carica papaya leaf extract in the socket or after prescribing systemic NSAID S following surgical extraction of third molarTimepoint: 1st, 4th and 7th day. SECONDARY OUTCOME: Compare and evaluate wound healing after placement of Carica papaya leaf extract in the socket or after prescribing systemic NSAID S following surgical extraction of third molarTimepoint: 1st, 4th and 7th day. INCLUSION CRITERIA: Patients who have not used any NSAIDS drugs 1 week before surgery Patients who do not have any underlying systemic conditions Patients who on evaluation have moderate surgical difficulty score on Pedersons index( SCORE 5 to 7) Patients with ASA status I and having normal bleeding & clotting time