Effect of tumeric extract supplementation on oxidative stress and inflammation after running

INTERVENTION: B01.650.940.800.575.912.250.618.937.900.166 D26.660 Dietary supplement Participants ingested 3 opaque capsules per day containing curcuma long l. extract (500 mg each, Supplemented group, 14 athletes) or placebo (cellulose microcrystalline, 500 mg each, Placebo group, 14 athletes). Two capsules were ingested with lunch and one with dinner for 29 days before the half‐marathon race. Immediately before the competition, participants were fed a standardized breakfast and consumed three capsules with it. SP6.051.227 CONDITION: C05.651.542 C23.550.470 G07.610.830 G11.427.410.568.610 Study with healthy humans performing a half marathon race Sports Nutritional Physiological Phenomena; Running; Inflammation; Myalgia; ; G07.610.830 ; G11.427.410.568.610 ; C23.550.470 ; C05.651.542 PRIMARY OUTCOME: A reduction on creatine kinase activity with the Curcuma longa L. extract, verified by the colorimetric method, based on a variation of at least 5% in pre and post‐intervention measurements. A reduction on myoglobin concentrations with the Curcuma longa L. extract, verified by the Enzyme‐Linked Immunosorbent Assays (ELISA) method, based on a variation of at least 5% in pre and post‐intervention measurements. SECONDARY OUTCOME: A reduction on muscle soreness with the Curcuma longa L. extract, verified by biceps femoris muscle palpation and stretching, based on a variation of at least 5% in pre and post‐intervention measurements. An increase on interleukin‐10 concentrations with the Curcuma longa L. extract, verified by the Enzyme‐Linked Immunosorbent Assays (ELISA) method, based on a variation of at least 5% in pre and post‐intervention measurements. INCLUSION CRITERIA: Men, eutrophic, aged between 25 and 50 years, amateur runners