Efficacy of High-Dose Continuous Intravenous Magnesium Sulfate Infusion vs Standard Intravenous Magnesium Sulfate Therapy in Status Asthmaticus in the ED

The goal of this clinical is to compare treatment outcomes between high dose continuousIV Magnesium and standard therapy in the management of acute exacerbation of asthma inthe emergency department. Participants will random assign to either high dose continuousIV drip or standard infusion. Participants in the intervention group received high‐dose50% magnesium sulfate (MgSO4), consisting of 2 g + normal saline (NSS) 100 mladministered intravenously over 30 minutes, followed by MgSO4 6 g + NSS 350 ml infusedover 3.5 hours (approximately 40‐50 mg/kg/h). In contrast, participants in the controlgroup received standard‐dose 50% MgSO4, consisting of 2 g + NSS 100 ml administeredintravenously over 30 minutes, followed by a NSS 350 ml infusion over 3.5 hours.Measurements include symptom severity, respiratory rate, oxygen saturation, and pulmonaryfunction tests. Primary endpoints are ED stay length, hospital admission, and ED revisitwithin 48 hours post‐discharge. Adverse events are documented.