Height Adjusted Versus Standardized Dose of Bupivacaine for Spinal Anesthesia

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2022
General anesthesia during pregnancy is associated with several major risks including unanticipated difficult airway, pulmonary aspiration, and specific anesthetic effects on the newborn. Thus, intrathecal anesthesia is the technique of choice for cesarean section. Nevertheless, the main side effect of intrathecal anesthesia is arterial hypotension which depend mainly on the dose of local anesthetic administered intrathecally. To date there is no guidelines nor evidences whic help the anesthetist to precisely estimate the required dose. Most often a \"standardized dose\" of 8 to 10 mg of bupivacaine is administered. However, some data suggest that a lower dose may be administered resulting in less frequent arterial hypotension. Nevertheless, a well designed randomized study is lacking.
Epistemonikos ID: e6a8b254d4ea05ff47f8c58213d31e58b532ed1e
First added on: May 10, 2024