Clinical observation of prevention of influenza A (H1N1) by Qingjie Fanggan Granules

Objective: To observe the clinical efficacy and safety of Qingjie Fanggan Granules in preventing influenza A (H1N1). Methods: 200 cases of close contacts or susceptible people of influenza A H1N1 influenza were selected and divided into control group and observation group according to the random number table method, with 100 cases in each group. The observation group took 3 consecutive days of Qingjie Fanggan Granules during the H1N1 influenza epidemic, and the control group did not take any medicine. Compare and analyze the infection rate of the two groups of subjects within 30 days, and observe whether there are any adverse reactions. Results: After preventive administration, there were 9 cases in the observation group infected with H1N1 influenza, with a total infection rate of 9%; a total of 23 cases in the control group were infected with H1N1 influenza, with a total infection rate of 23%, indicating that the difference in efficacy between the two groups was statistically significant. Significance (P0.01); the percentage of lymph in 23 cases in the control group was significantly higher than that in the observation group (P0.01); 23 cases in the control group had fever symptoms, nasal congestion symptoms and muscle soreness scores were significantly higher than those in the observation group 9 cases ( P0.05). During the trial period, no adverse events were found. Conclusion: Qingjie Fanggan granules have the functions of clearing heat and detoxification, invigorating the spleen and qi, nourishing yin and strengthening the body, which can improve the body's righteousness and resist the invasion of external evils. Taking this product during the influenza epidemic can effectively prevent the infection of H1N1 influenza. The role of traditional Chinese medicine to prevent disease first.