Impact of Chia Seeds on Human Breast Milk Composition

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
The investigators\' over-arching hypothesis is that mechanical and compositional properties of chia seeds supplemented during lactation diminish obesity-induced intestinal inflammation and barrier dysfunction. The investigators hypothesize these changes will result in: 1) reduced maternal systemic inflammation (serum CRP and IL-6) and increased gut microbial diversity and richness, 2) reduced HM fat and inflammatory markers, metrics the research team have demonstrated differ in tandem with maternal metabolic health and 3) improved infant growth/body composition. To test these hypotheses, investigators will evaluate chia seed supplementation during lactation in a 6wk multi-site pilot RCT (Aim 1) and through translational studies using human enteroids (Aim 2).
Epistemonikos ID: e61750bc03a73ed47d8dfefba5aa6257482ba4d9
First added on: Jan 16, 2026