Acupuncture to Reduce Signs of Inflammation in Participants With Chronic Low Back Pain

Background: - Acupuncture is a traditional Chinese medical treatment. Thin needles are used to stimulate specific points in the body. Previous studies have found that acupuncture can be useful in treating low back pain. This study will explore how acupuncture affects low back pain. Researchers will look at blood samples for changes in different chemicals related to inflammation and pain. Objectives: - To test the effect of acupuncture on blood chemicals associated with chronic low back pain. Eligibility: * People at least 18 years of age who have chronic low back pain. * Those who have had back surgery or had acupuncture for any medical condition may not participate. Design: * This study requires eight visits over 2 to 3 weeks. Each visit will take 1.5 to 2 hours. * At the first study visit, participants will give a medical history and complete two questionnaires about their low back pain. They will also spend 30 minutes lying down on a bed, relaxing quietly. * The next visits will occur every 2 to 3 days for the next 2 weeks. Participants will receive 30 minutes of either sham or standard acupuncture. Sham acupuncture will mimic the standard procedure, but no needles will be used. The standard procedure will be performed in the same location. A licensed, experienced acupuncturist will insert small disposable needles into acupuncture sites on the back, arms, and legs. Those in the study will not know whether they are receiving the sham or the standard acupuncture procedure. * At some visits, participants will provide blood samples for testing. At every visit, participants will complete the questionnaires about low back pain.