A Phase IV Clinical Trial of EMPYNASE P Tablets 18000 in Patients with ankle swelling after lateral ankle sprain injuries

INTERVENTION: EMPYNASE group EMPYNASE, The RICE (rest, ice, compression, and elevation) regimen & Flurbiprofen patch application. Placebo group Placebo, The RICE (rest, ice, compression, and elevation) regimen & Flurbiprofen patch application. CONDITION: ankle swelling after lateral ankle sprain injuries. PRIMARY OUTCOME: Change in ankle‐foot volume from baseline. SECONDARY OUTCOME: Change in ankle circumference from baseline. INCLUSION CRITERIA: ‐ Patient with ankle sprain after lateral ankle sprain injuries. ‐ Patient with ankle swelling after lateral ankle sprain injuries. ‐ Patient who can be measured the ankle‐foot volume 24‐60 hours after lateral sprain injuries.