Electronic Pre-exposure Prophylaxis (PrEP) Initiation and Maintenance Home Care System

The premise for the study is that a tailored approach for YMSM from rural and small town areas, addressing known barriers of transportation, access to providers, and privacy, is most likely to yield high levels of PrEP initiation and persistence in care. The study sites are Alabama, Georgia, North Carolina, and Mississippi. Using a smartphone application (app), participants assigned to the intervention will receive and maintain a PrEP prescription without needing to leave their home (excepting pharmacy pick‐up in some cases) ‐ achieved through app‐based surveys/screenings, telemedicine consultations, and home specimen self‐collection.