Montelukast in the Treatment of Bronchiolitis, A Multi-center, Randomized, hree-blind, Placebo-controlled Trial

OBJECTIVE: To study the efect of montelukast for improving bronchial hyperresponsiveness (BHR) in treatment of bronchiolitis. METHODS: Four hundreds infants, 3 to 24 months old, hospitalized with acute bronchiolitis in three Hospitals (Urumqi Children’s Hospital, Pediatrics Department of First Ailiated Hospital of Xinjiang Medical University, and Pediatrics Department of Army General Hospital) from January, 2007 to January, 2008, were randomly assigned into four groups: placebo group ( RESULTS: =92), budesonide group ( CONCLUSIONS: =91), montelukast short-course group (7 days,