Prognostic evaluation of stable coronary disease throughout a score with clinical data and the exercise testing final result

Authors
Category Primary study
ThesisTese (Doutorado em Cardiologia). Universidade de São Paulo, Faculdade de Medicina
Year 2011
INTRODUCTION: The need to improve the exercise testing accuracy, lead the development of scores, which applicability were already widely recognized. OBJECTIVE: Prognostic evaluation of stable coronary disease throughout a new simplified score. METHODS: A new score was applied in 372 bi or triarterial coronary patients, 71,8% men mean age 59,5+9,07 years, randomized for percutaneous coronary intervention (PCI), coronary artery bypass graft surgery (CABG) and clinical treatment, with 5 years follow-up. Cardiovascular death was considered the primary outcome. Non-fatal myocardial infarction, death and re-intervention were considered the combined secondary outcome. The score was based on a previously validated equation, resulting from a sum of one point score for: male gender, infarction history, angina, diabetes, use of insulin and one point score for each decade of life after the age of 40 years. Positive exercise testing summed one additional point score. RESULTS: There were 36 deaths (10 in the PCI group, 15 in the CABG group and 11 in the clinical group), p=0.61. There were 93 combined events: 37 in the PCI group, 23 in CABG group and 33 in the clinical group (p=0.058). Two hundred and forty-seven patients presented a clinical score 5 points and 216 patients 6 points. The cut-off point 5 or 6 identified an increased risk, p=0.015 and p=0.012, respectively. The survival curve showed a different death incidence after the randomization when the score reached 6 points or more (p=0.07), and a distinct incidence of combined events between the patients with points score <6 and 6 (p=0.02). CONCLUSION: The new score showed to be consistent in the prognostic evaluation of stable multivessel coronary artery disease.
Epistemonikos ID: e347af09e4c92c447ecc67f3e7f3a456ab2ce304
First added on: Jan 18, 2025