The effect of nasal mupirocin, prior to percutaneous endoscopic gastrostomy (PEG), upon peristomal colonisation and infection

Authors
Category Primary study
Registry of TrialsISRCTN registry
Year 2004
INTERVENTION: Nasal mupirocin versus standard care (no prophylactic antibiotics). Mupirocin was administered for 5 days before PEG insertion. Nasopharyngeal swabs, PEG site appearance and bacteriology were recorded up to 10 days post‐PEG. CONDITION: Post‐percutaneous endoscopic gastrostomy sepsis ; Injury, Occupational Diseases, Poisoning ; Complications of procedures PRIMARY OUTCOME: Pilot: ; Will access the practicalities of the study design, the consistency of the scoring tool and also give an indication of the bacteriology of nasal colonisation, peristomal colonisation and infection within the proposed research setting.; ; Main: ; The primary outcome measure is that of perstomal infection. SECONDARY OUTCOME: Secondary outcomes of peristomal colonisation and risk factors for methicillin resistant staphylococcus aureus (MRSA) colonisation will also be measured. INCLUSION CRITERIA: Pilot study of 20 patients recruited, pilot study of 10 controls
Epistemonikos ID: e336fb6455aac50b4d9bd8c2f4659b4b0b91210c
First added on: Aug 21, 2024