Effect of Fruit Elicitation With Melatonin on Human Health

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2025
The goal of this clinical trial is to learn if treating fruits with melatonin helps the body absorb and use healthy plant compounds. It will also learn how much melatonin from the fruits is taken up by the body. The main questions it aims to answer are: * Does melatonin treatment of fruits raise the amount of healthy compounds the body absorbs? * Does melatonin from treated fruits appear in urine after eating them? Researchers will compare juice made from melatonin-treated fruits to juice made from untreated fruits to see if melatonin changes absorption. Participants will: * Follow a special low-plant-compound diet for 3 days before each test day * Drink 300 grams of juice from treated or untreated fruit while fasting * Provide urine samples before and after drinking the juice * Return 15 days later to switch to the other juice type * Repeat this process with lemon, blood orange, and cherry
Epistemonikos ID: e298a09e919846bd04e015305e156ad2fae7ce22
First added on: Sep 26, 2025