CML IV - Chronic phase chronic myeloid leukaemia/CML 2000

INTERVENTION: Cycle of chemotherapy and an autograft with subsequent IFN/IFN therapy alone CONDITION: Leukaemia ; Cancer ; Chronic myeloid leukaemia PRIMARY OUTCOME: Length of survival, quality of life, cytogenetic response SECONDARY OUTCOME: Not provided at time of registration INCLUSION CRITERIA: 1. The interval from diagnosis to registration does not exceed 3 months (if received only hydroxyurea in these 3 months proceed to register, if alpha Interferon (IFN) has been given contact co‐ordinators) 2. They are aged 18‐60; they have newly diagnosed CML 3. They have acceptable criteria for chronic phase 4. They have given informed consent and are willing to be randomised, there is no contraindication to collection of blood or marrow progenitor cells before treatment is commenced 5. They are not pregnant