Antihistamine for Prevention of HTR After Blood Primed CPB

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This study will be a randomized, double-blinded, placebo-controlled study conducted at a university hospital. Forty children undergoing elective repair of a congenital heart defect will be included. The patients will be randomly allocated (20 patients per group) to receive a single intravenous dose of combined chlorpheniramine or normal saline immediately after separation from CPB, before protamine administration.
Epistemonikos ID: e067edb5148ad7646f9f9c2c85c21929c3b005ca
First added on: Apr 18, 2026