Clinical study to evaluate the effectiveness of rectal culture before prostate biopsy to prevent postoperative bacterial prostatitis, multicenter, randomized controlled trial in Japan

INTERVENTION: arm using selective media for rectal cultoure Culture from rectal swab is evaluated before prostate biopsy. If resistant bacteria are confirmed, piperacin/tazobactam 4.5g will administered 30 minutes before biopsy and 4 hours after biopsy. If not detected, levofloxacin 500mg is orally given 30minutes before biopsy. control arem levofloxacin 500mg is orally given 30minutes before biopsy. CONDITION: acute bacterial prostatitis PRIMARY OUTCOME: Incidence rate of acute bacterial prostatitis. SECONDARY OUTCOME: Sensitivity and specificity of simple medium, severity at the onset of prostatitis. INCLUSION CRITERIA: