Comparative effect of two methods of relaxation and meditation on serum levels of IL-2, TNF-a, IL-17A and IL-23 cytokines

INTERVENTION: Intervention 1: Intervention group 1: A relaxation program will be planned and implemented in seven stages for the relaxation group, the steps of which will be:1. Identify the muscles and muscle groups of the case, 2‐ Training on progressive muscle relaxation technique using its explanation and practical presentation by the researcher,3‐ Answering the patient's questions about the relaxation technique 4‐ Performing the technique by the researcher using an audio tape, or educational CD 5‐ Performing the technique by the patients along with the researcher, 6‐ Statement of difference in physical and mental feelings of samples after relaxation 7‐ Performing the technique by samples and under the supervision of the researcher. In relaxation, patients will be asked to first shrink and then loosen the muscles of the muscles of the foot to the muscles of the face, including 16 muscles. Patients relax their muscles by counting up to number 5 and then relaxing by counting up to 10.The same steps will be repeated for the legs, legs, thighs, abdomen, chest, hips, arms and forearms, arms, shoulders, neck, forehead, tongue and jaw, eyes and face until all of their bodies Loose integrated.At the same time, patients breathe deeply during relaxation. The state of choice for gradual relaxation is lying. The patient will perform this exercise until the difference between the contraction and the muscle tone is felt and expressed.In this way, the method will be taken and can take this method alone and using a tape. After ensuring the correct understanding and correctness of the procedure, audio cassettes and CDs will be provided to patients for the implementation of relaxation steps. And they spend three months (three times a week) one day in a row and for a half an hour under the supervision of the researcher (a total of 36 sessions). Intervention 2: Intervention group 2: To perform meditation, the patient is asked to be in a comfortable position and perform a deep inhale with 3 numbe CONDITION: Coronary Artery Disease. ; Chronic ischemic heart disease PRIMARY OUTCOME: Measuring the serum level of IL‐17A. Timepoint: Before the start of the study and three months after the start of the study. Method of measurement: ELISA test. Measuring the serum level of IL‐2. Timepoint: Before the start of the study and three months after the start of the study. Method of measurement: ELISA test. Measuring the serum level of IL‐23. Timepoint: Before the start of the study and three months after the start of the study. Method of measurement: ELISA test. Measuring the serum level of TNF‐a. Timepoint: Before the start of the study and three months after the start of the study. Method of measurement: ELISA test. INCLUSION CRITERIA: Known coronary artery disease (based on medical records); History of admission in section CCU Expression of willingness to participate in the study