Safety and Efficacy of DIT101 in Relapsed or Refractory Hematologic Malignancies

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2026
This study is a single-arm, open-label clinical trial designed to evaluate the safety and tolerability of DIT101 in adults with relapsed or refractory hematologic malignancies and to explore its potential anti-tumor effects. DIT101 is an investigational in vivo CAR-T cell therapy administered by intravenous infusion. After administration, it is intended to generate CAR-T cells within the patient\'s body that can recognize and attack tumor cells. Unlike approved autologous CAR-T therapies, DIT101 does not require collection and ex vivo genetic modification of the participant\'s own cells. The study includes a screening period, DIT101 infusion treatment, a post-treatment intensive follow-up period of approximately 6 months, and a long-term follow-up period of up to 2 years, with visits every 3-6 months.
Epistemonikos ID: dfb62dc59b9677cb756e7a900eca8fcebd8036a3
First added on: Apr 01, 2026