Oral Immunotherapy for Children With Peanut Allergy

Authors
Category Primary study
Registry of TrialsClinicalTrials.gov
Year 2026
This clinical trial aims to investigate if oral immunotherapy can help children with peanut allergy tolerate peanut. Children aged 6 months to 4 years can take part in the trial. Main question: What percentage of children can tolerate peanut after oral immunotherapy, compared with children who avoid peanut? Children are assigned to these two groups by chance. Children receiving oral immunotherapy will: * Take a small, increasing amount of peanut daily for 1-1.5 years * Attend clinic or online visits each time the dose is increased * Record missed doses All children will: * Provide blood samples to measure allergy-related markers * Undergo an oral food challenge with peanut after 1-1.5 years to assess how much they can tolerate * Report allergic reactions (parent-reported) * Complete questionnaires (parent-reported) * Participate in an end-of-study telephone interview with an allergy nurse (parent-reported)
Epistemonikos ID: dec429d9f234a10d6257171934b2b31479bd7542
First added on: Oct 27, 2026