The impact of indocyanine green (ICG) angiography in multiple diagnostic imaging for the management of exudative age-related macular degeneration (ARMD): a single blind prospective randomised controlled trial of fluorescein angiography vs FA & ICG

INTERVENTION: Interventions are fluorescein angiography compared with fluorescein angiography and indocyanine green angiography. Added 05/09/2008: trial was stopped due to new treataments available. CONDITION: Eye Diseases: Age‐related macular degeneration (ARMD) ; Eye Diseases ; Age‐related macular degeneration (ARMD) PRIMARY OUTCOME: Moderate and severe visual loss defined as loss of three lines or 15 letters (doubling of visual angles) and loss of 6 lines or 30 letters respectively, on a log MAR visual acuity chart, at 4,8 and 12 months. SECONDARY OUTCOME: 1. ICG rates modification of fluorescein based diagnosis and management; 2. Specificity and sensitivity of ophthalmic signs predictive of ICG findings INCLUSION CRITERIA: 240 patients, of whom 24 are estimated to have retinal angiomatous proliferation (RAP).