Novel Liquid-Helium-Free Magnetoencephalography Assisted Motor Function Preservation in Meningioma Resection

Authors
Category Primary study
Registry of TrialsChinese Clinical Trial Register
Year 2026
INTERVENTION: Experimental group:In addition to the standard clinical management pathway, preoperative motor mapping was performed using helium‐free MEG. During surgery, the OPM‐MEG motor mapping results were integrated into the neuro‐navigation system, and tumor resection was performed under neuro‐navigation guidance and with direct cortical stimulation (DCS) monitoring;;Control Group:Prior to surgery, participants underwent relevant examinations in accordance with standard clinical protocols (which may include fMRI, DTI, etc.). During surgery, routine imaging data were fused into the neuro‐navigation system, and tumor resection was performed under navigation guidance and with direct cortical stimulation (DCS) monitoring.; CONDITION: Patients with preoperatively suspected supratentorial meningiomas on imaging, whose lesions are adjacent to the precentral gyrus PRIMARY OUTCOME: The incidence of new‐onset motor dysfunction assessed at the 3‐month postoperative follow‐up; SECONDARY OUTCOME: Incidence of motor dysfunction 7 days postoperatively;Incidence of severe motor dysfunction at 7 days and 3 months postoperatively;Consistency Between MEG Localization and Direct Cortical Stimulation (DCS) Localization;Extent of Tumor Resection (EOR);Incidence of Adverse Events/Serious Adverse Events;Incidence of Device‐Related Discomfort;Device Defects; INCLUSION CRITERIA: (1) Aged 18–75 years; gender is not a factor; (2) Patients with a presumptive preoperative imaging diagnosis of supratentorial meningioma who are scheduled to undergo neurosurgical treatment; (3) The tumor’s area of abnormal signal on MRI contrast‐enhanced imaging covers or compresses the precentral gyrus or paracentral lobule; (4) Patients who are able to understand and cooperate with this study and have signed an informed consent form.
Epistemonikos ID: de7c1871e0b16a9bda720e58e587b891457a6f97
First added on: Sep 12, 2026