The effect of heparin on lung function following cardiopulmonary bypass.

INTERVENTION: A double blind randomised trial comparing intravenous heparin versus placebo (5% glucose). The infusion will be commenced 8 ‐ 10 hours prior to commencement of surgery and ceased prior to the insertion of lines or sternotomy. CONDITION: Lung injury following cardiac surgery. PRIMARY OUTCOME: Alveolar dead space SECONDARY OUTCOME: Plasma levels of prothrombin fragments, t.PA, D. dimer INCLUSION CRITERIA: Adult patients undergong elective cardiac surgery for coronary artery bypass grafting with cardiopulmonary bypass.