Curcumin for COVID-19 Pre Exposure Prophylaxis

INTERVENTION: Intervention1: Curcumin: Oral Curcumin capsule 500 mg twice daily (morning , evening ) for 12 weeks Control Intervention1: Placebo: Placebo Capsule oral twice daily morning evening for 12 weeks CONDITION: PRIMARY OUTCOME: 1. SARS‐CoV 2 infection rate Using RTPCRTimepoint: 12 weeks SECONDARY OUTCOME: Frequency of respiratory tract infections during course of study using the Wisconsin Upper Respiratory Symptom Survey ; Timepoint: 12 weeks Number of participants with treatment‐related adverse events as assessed by CTCAE v5.0.Timepoint: 12 weeks INCLUSION CRITERIA: People at risk of SARS‐CoV 2 infection ( healthcare professionals , attendants of COVID patients , non COVID patients admitted in hospitals or his risk groups like elderly , cardiovascular patients , diabetes , obesity ) Not having a previous COVID19 diagnosis Not having experienced COVID19 symptoms since 30 th Jan 2020. Not having taken any pre‐exposure prophylaxis ( HCQ , any other medication or Ayurvedic preparation or food supplement ) Having a negative SARS‐CoV 2 test before randomisation