A Study in patients with headache after spinal needle procedures: comparing a nasal nerve block and theophylline tablets for headache relief

Authors
Category Primary study
Registry of TrialsClinical Trials Registry - India
Year 2026
INTERVENTION: Intervention1: Transnasal sphenopalatine ganglion block: Patient having PDPH symptoms are treated with non invasive method of blocking of sphenopalatine ganglion block through trannasal route using 5 mL of 4% lignocaine solution each side. Intervention2: Oral theophylline tablets: Patients having PDPH symptoms are given oral TAB THEOPHYLLINE 5‐10 mg/kg Control Intervention1: Oral theophylline tablet: Patient with PDPH symptoms are given oral theophylline tablets CONDITION: Health Condition 1: R298‐ Other symptoms and signs involvingthe nervous and musculoskeletal systems PRIMARY OUTCOME: To compare the efficacy of transnasal sphenopalatine ganglion block vs Oral Theophylline by measuring VAS scoreTimepoint: 48 hours SECONDARY OUTCOME: To Asses patient satisfaction scoreTimepoint: 24 hours To assess the requirement of rescue analgesiaTimepoint: 24 hours To evaluate the hemodynamic changesTimepoint: 30 minutes INCLUSION CRITERIA: ASA Physical status 1, 2 and 3 Patients reporting with PDPH
Epistemonikos ID: dd9b40790dc1f5fcfbce6da866d0b5c8cad593bb
First added on: Jul 25, 2026