VRelax for reducing stress

INTERVENTION: VRelax The VRelax tool is used with a Samsung Galaxy S6 or S7 smartphone that is connected to a head mounted display, the Samsung Gear VR. When activated, the participant is on a beach, from which he/she can choose where to go. The 360o videos of relaxing environments include nature landscapes, a coral reef, a drone flight, a scuba diving experience with dolphins, a mountain meadow with animals, and a session of Tibetan sound bowls. Participants can navigate through the environments by looking at hotspots within their field of view, that will be activated after three seconds. 3D audio is played with headphones. One of the hotspots activates a voiceover with guided meditation or a progressive relaxation exercise. In some of the environments, interactive visual elements are added, such as underwater air bubbles that pop when you look at them. Participants receive a VRelax set to take home, including Gear VR, smartphone and headphones. They are instructed how to use it and are invited to use the VRelax app as often as they wish, but minimally once daily for at least 10 minutes. After 10 days, they return the VR set to the study team. Standard relaxation As control intervention, participants receive headphones and a USB stick with 2D nature videos with spoken guided meditation and progressive relaxation exercises. They can play the tracks on devices they have at home (desktop or laptop computer). They are instructed how to use it and are invited to use the USB stick as often as they wish, but minimally once daily for at least 10 minutes. After 10 days, they return the headphones and USB stick to the study team. CONDITION: Burnout , Depressive Disorder , Bipolar disorder, Anxiety disorders, Psychotic disorders ; ; PRIMARY OUTCOME: 1. The immediate effect on level of subjective stress, measured with Visual Analogue Scales (range 0‐100) embedded in the VRelax and standard relaxation tools. Eight Ecological Momentary Assessment items are selected that have been used in previous studies.; ; ; ; 2. VRelax user experiences are collected with interviews (previous experiences with relaxation exercises and VR, expectations met or not, ease and pleasure of using, quality, intensity, use of interactive elements), questionnaires (presence [IGroup Presence Questionnaire]), cyber sickness [Simulator Sickness Questionnaire SSQ]) and logging of use, including frequency, duration, time of day, type of environment visited. SECONDARY OUTCOME: Short‐term effects on perceived stress: ; ; ‐ Perceived Stress Scale assesses stress level over the past week, will be administered at baseline and after both intervention periods. ; ; ; ; Symptoms of depression, anxiety and psychosis: ; ; ‐ Depression: Inventory of Depressive Symptomatology‐Self‐Rated (IDS‐SR): measures the severity of depressive symptoms on a 30 item questionnaire. ; ; ‐ Anxiety: Beck Anxiety Inventory (BAI): measures the severity of anxiety on a 21 item questionnaire. ; ; ‐ Paranoia: Green Paranoid Thoughts Scale (GPTS): measures two dimensions of paranoid thinking with a 20 item questionnaire: ideas of social reference and ideas of social persecution. ; ; ; ; Use of medication: ; ; Names and daily dosage of medication (both prescribed and over‐the‐counter medication) are listed at baseline and reported over the ten‐day periods by the participants. ; ; ; ; Use of psychoactive substances: ; ; Units of coffee, tea, cigarettes, alcohol, cannabis, illicit drugs are assessed at baseline and reported over the ten‐day periods by the participants. INCLUSION CRITERIA: • Currently receiving ambulatory treatment for surmenage or burn‐out, or DSM‐5 depressive disorder, bipolar disorder, anxiety disorder or psychotic disorder. • At least moderate level of perceived stress, based on self‐report or clinician report • Age >18