Protective Effect of Tranexamic Acid on Shedding of the Endothelial Glycocalyx in Patients Undergoing Spinal Fusion Surgery

Authors
Category Primary study
Registry of Trialsclinicaltrials.gov
Year 2018
The aim of this study was to determine whether the administration of tranexamic acid in patients undergoing lumbar spinal fusion surgery can inhibit damage in endothelial glycocalyx layer. As a prospective double blinded randomized placebo‐controlled trial, the investigators detect and compare the changes in concentrations of serum syndecan‐1 and heparan sulfate before and after surgery.
Epistemonikos ID: db50f9d189dafc8cfda5bc2629bcbb89c4579b97
First added on: May 21, 2024